| 摘要: |
| 观察小剂量口服阿托伐他汀钙较长时间后支气管扩张症患者的临床疗效。纳入40例确诊为支气管扩张症的患者，对照组给予常规治疗，治疗组在常规治疗的同时给予阿托伐他汀钙片10 mg口服，每晚1次，总疗程为3个月。观察患者的急性加重次数、肺功能指标、24 h的痰总量、咳嗽症状评分和呼吸困难指数。与对照组比较，治疗组患者的急性加重次数、24 h痰总量、咳嗽症状评分及呼吸困难指数均有显著性改善，而肺功能无显著性改善。小剂量口服阿托伐他汀钙较长时间可减少患者的急性加重次数、24 h痰总量、减轻咳嗽及呼吸困难症状，改善支气管扩张症患者的临床症状。 |
| 关键词: 阿托伐他汀钙片 支气管扩张 临床疗效 |
| DOI：10.11851/j.issn.1673-1557.2017.04.007 |
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| Therapeutic effect of atorvastatin calcium on bronchiectasis |
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LI Lan,LI Hanchun and TANG Fengming
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| Abstract: |
| To observe the clinical efficacy of long-term and low-dose oral atorvastatin calcium in bronchiectasis Forty bronchiectasis patients were included in our study The control group was given conventional treatment while the treatment group was given 10 mg atorvastatin calcium tablet orally once every night combined with conventional treatment for 3 months The frequency of acute exacerbation， pulmonary function indexes， total 24-hour sputum volume and cough symptom score were observed in all patients The frequency of acute exacerbation，total 24-hour sputum volume， cough symptom score and dyspnea index were improved significantly while pulmonary function was not significantly improved in the treatment group Long-term and low-dose oral atorvastatin calcium can reduce the frequency of exacerbations， 24-hour total sputum volume and relieve dyspnea and cough |
| Key words: atorvastatin calcium bronchiectasis clinical efficacy |
